Rb1.com.br - The RB1 Story: Characterization and Cloning of the First Tumor

Provided by Alexa ranking, rb1.com.br has ranked N/A in N/A and 9,382,744 on the world. rb1.com.br reaches roughly 328 users per day and delivers about 9,837 users each month. The domain rb1.com.br uses a Commercial suffix and it's server(s) are located in N/A with the IP number 187.45.163.13 and it is a .com.br domain.

WEBNov 1, 2019 · This article reviews the long history of RB1 gene research, characterization, and cloning, and also discusses recent advances in retinoblastoma genetics that have grown out of this foundational work. Keywords: retinoblastoma, tumor suppressor gene, cancer genetics, gene cloning, genetic testing. Go to:

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The RB1 Story: Characterization and Cloning of the First Tumor
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6895859/

WEBNov 1, 2019 · This article reviews the long history of RB1 gene research, characterization, and cloning, and also discusses recent advances in retinoblastoma genetics that have grown out of this foundational work. Keywords: retinoblastoma, tumor suppressor gene, cancer genetics, gene cloning, genetic testing. Go to:

DA: 92 PA: 39 MOZ Rank: 91

Pan-cancer molecular analysis of the RB tumor suppressor pathway …
nature.com

https://www.nature.com/articles/s42003-020-0873-9

WEBApr 2, 2020 · The retinoblastoma tumor suppressor gene ( RB1) plays a critical role in coordinating multiple pathways that impact cancer initiation, disease progression, and therapeutic responses. Here we...

DA: 41 PA: 41 MOZ Rank: 22

Retinoblastoma: Etiology, Modeling, and Treatment - PMC
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465685/

WEBAug 16, 2020 · Retinoblastoma is a retinal cancer that is initiated in response to biallelic loss of RB1 in almost all cases, together with other genetic/epigenetic changes culminating in the development of cancer. RB1 deficiency makes the retinoblastoma cell-of-origin extremely susceptible to cancerous transformation, and the tumor cell-of-origin appears to ...

DA: 72 PA: 16 MOZ Rank: 92

The Cars - Red Bull Racing
redbullracing.com

https://www.redbullracing.com/int-en/cars/rb1/

WEBOur maiden challenger was brought to life in 2005. With the distinctive dark blue paint scheme accompanied with the yellow nosecone and engine cover logo, which still features to this day, it was our first step into Formula One. The mighty Cosworth TJ2005 normally-aspirated 3.0 litre V10 engine powered the Team in its first season.

DA: 45 PA: 70 MOZ Rank: 65

RB1, development, and cancer - PMC - National Center for …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691055/

WEBThe RB1 gene is the first tumor suppressor gene identified whose mutational inactivation is the cause of a human cancer, the pediatric cancer retinoblastoma. The twenty five years of research since its discovery has not only illuminated a general role for RB1 in human cancer, but also its critical importance in normal development.

DA: 44 PA: 86 MOZ Rank: 62

Retinoblastoma Origins and Destinations | NEJM
nejm.org

https://www.nejm.org/doi/full/10.1056/NEJMra1803083

WEBApr 17, 2024 · N Engl J Med 2024;390: 1408 - 1419. DOI: 10.1056/NEJMra1803083. VOL. 390 NO. 15. Retinoblastoma is a childhood retinal cancer that occurs in approximately 6 of 100,000 live births, with 250 to 300 ...

DA: 93 PA: 39 MOZ Rank: 62

RB1 loss in castration-resistant prostate cancer confers
nature.com

https://www.nature.com/articles/s41388-021-02135-3

WEBJan 3, 2022 · Genomic loss of RB1 is a common alteration in castration-resistant prostate cancer (CRPC) and is associated with poor patient outcomes. RB1 loss is also a critical event that promotes the...

DA: 87 PA: 32 MOZ Rank: 91

Cancers | Free Full-Text | Therapeutic Strategies for RB1-Deficient
mdpi.com

https://www.mdpi.com/2072-6694/16/8/1558

WEB5 days ago · The retinoblastoma (RB) transcriptional corepressor 1 (RB1) is a critical tumor suppressor gene, governing diverse cellular processes implicated in cancer biology. Dysregulation or deletion in RB1 contributes to the development and progression of various cancers, making it a prime target for therapeutic intervention. RB1′s canonical function in …

DA: 44 PA: 82 MOZ Rank: 94

Role of RB1 in neurodegenerative diseases: inhibition of post …
nature.com

https://www.nature.com/articles/s41420-024-01955-y

WEB5 days ago · A RB1 mutation rates by DNA sequence data in blood samples from PD (n = 189), AD (n = 33), HD (n = 69), and ALS (n = 75) patients from the Guangzhou KingMed Diagnostics Group Co. B Detailed ...

DA: 58 PA: 71 MOZ Rank: 8

RB1 Gene - GeneCards | RB Protein | RB Antibody
genecards.org

https://www.genecards.org/cgi-bin/carddisp.pl?gene=RB1

WEBApr 3, 2024 · RB1 (RB Transcriptional Corepressor 1) is a Protein Coding gene. Diseases associated with RB1 include Retinoblastoma and Small Cell Cancer Of The Lung. Among its related pathways are Defective binding of RB1 mutants to E2F1,(E2F2, E2F3) and Regulation of activated PAK-2p34 by proteasome mediated degradation.

DA: 11 PA: 35 MOZ Rank: 49

Alexa Rank

GLOBAL RANK

9,382,744

Alexa Reach

0.0000144742

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Alexa Rank Country N/A

N/A

Daily Unique Visitors

328

Monthly Unique Visitors

9,837

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2,104

Indonesia

1,646

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535

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475

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430

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376

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316

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298

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298

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260

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186

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181

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178

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148

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144

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138

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130

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120

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110

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100

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DNS Record

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rb1.com.br	MX	IN	300	Pri: 10 Target: ALT3.ASPMX.L.GOOGLE.COM
rb1.com.br	MX	IN	300	Pri: 5 Target: ALT2.ASPMX.L.GOOGLE.COM
rb1.com.br	MX	IN	300	Pri: 5 Target: ALT1.ASPMX.L.GOOGLE.COM
rb1.com.br	MX	IN	300	Pri: 10 Target: ALT4.ASPMX.L.GOOGLE.COM
rb1.com.br	A	IN	300	Ip: 187.45.163.13
rb1.com.br	SOA	IN	600	Mname: server1.vialink.com.br Rname: hostmaster.vialink.com.br Serial: 2021092901 Refresh: 3600 Retry: 900 Expire: 1209600 Minimum-ttl: 3600
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rb1.com.br	NS	IN	600	Target: server2.vialink.com.br
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rb1.com.br	TXT	IN	300	Txt: v=spf1 include:_spf.google.com include:_spf.google.com include:_netblocks.google.com include:_netblocks2.google.com include:_netblocks3.google.com -all Entries_0: v=spf1 include:_spf.google.com include:_spf.google.com include:_netblocks.google.com include:_netblocks2.google.com include:_netblocks3.google.com -all

Hosting and Whois Zone

IP	187.45.163.13
Domain infomation	% Copyright (c) Nic.br % The use of the data below is only permitted as described in % full by the Use and Privacy Policy at https://registro.br/upp , % being prohibited its distribution, commercialization or % reproduction, in particular, to use it for advertising or % any similar purpose. % 2024-04-24T10:32:49-03:00 - IP: 2604:a880:4:1d0::5bb:800f domain: rb1.com.br owner: Cond do Ed Centro Empresarial Internacional Rio ownerid: 35.794.064/0001-96 responsible: Gilson Paes country: BR owner-c: RIKMA2 tech-c: VSTLT40 nserver: server1.vialink.com.br nsstat: 20240422 AA nslastaa: 20240422 nserver: server2.vialink.com.br nsstat: 20240422 AA nslastaa: 20240422 created: 19961023 #19902 changed: 20220920 expires: 20241023 status: published nic-hdl-br: RIKMA2 person: Ricardo K. Marcondes e-mail: [email protected] country: BR created: 20090207 changed: 20230410 nic-hdl-br: VSTLT40 person: Vialink Solu��es de Tecnologia Ltda e-mail: [email protected] country: BR created: 20220216 changed: 20230510 % Security and mail abuse issues should also be addressed to % cert.br, http://www.cert.br/ , respectivelly to [email protected] % and [email protected] % % whois.registro.br accepts only direct match queries. Types % of queries are: domain (.br), registrant (tax ID), ticket, % provider, CIDR block, IP and ASN.