Antibodydrugconjugates.us - Exploring the next generation of antibody–drug conjugates

nature.com

https://www.nature.com/articles/s41571-023-00850-2

WEBJan 8, 2024 · Antibody–drug conjugates (ADCs) have emerged as a promising class of cancer therapeutics. An ADC consists of a monoclonal antibody and a potent cytotoxic payload connected through a chemical...

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nature.com

https://www.nature.com/articles/d41573-024-00064-w

WEBApr 16, 2024 · The antibody–drug conjugate landscape. Antibody–drug conjugates (ADCs) have become a key therapeutic modality in oncology, spurred by superior clinical profiles …

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nature.com

https://www.nature.com/articles/s41392-022-00947-7

WEBMar 22, 2022 · Antibody–drug conjugate (ADC) is typically composed of a monoclonal antibody (mAbs) covalently attached to a cytotoxic drug via a chemical linker.

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wikipedia.org

https://en.wikipedia.org/wiki/Antibody%E2%80%93drug_conjugate

OverviewMechanism of actionHistoryComponents of an ADCPayloadsLinkersAnything Drug ConjugatesResearchAntibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. Unlike chemotherapy, ADCs are intended to target and kill tumor cells while sparing healthy cells. As of 2019, some 56 pharmaceutical companies were developing ADCs. ADCs are complex molecules composed of an antibody linked to a biologically …

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ascopubs.org

https://ascopubs.org/doi/10.1200/EDBK_390094

WEBMay 25, 2023 · Antibody-drug conjugates (ADCs) are a rapidly emerging class of therapeutic agents that combine the target specificity of a monoclonal antibody (mAb) …

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nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628511/

WEBOct 27, 2021 · Antibody-drug conjugates (ADCs) are innovative biopharmaceutical products in which a monoclonal antibody is linked to a small molecule drug with a stable linker. …

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nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10417123/

WEBJul 30, 2023 · Antibody–drug conjugates (ADCs) are an innovative family of agents assembled through linking cytotoxic drugs (payloads) covalently to monoclonal …

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nature.com

https://www.nature.com/articles/s41392-022-00947-7

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nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8538104/

WEBSep 29, 2021 · Antibody-drug conjugates (ADCs) comprise a fast-expanding therapeutic modality designed to target disease cells, sparing the adjacent healthy tissues.

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