overall response rate | The Clinical Viewpoint: Definitions, Limitatio

Keyword	CPC	PCC	Volume	Score	Length of keyword
overall response rate	1.08	1	4459	15	21
overall	1.64	0.1	9440	4	7
response	0.68	0.2	7564	51	8
rate	1.28	0.8	1567	2	4

Keyword	CPC	PCC	Volume	Score
overall response rate	1.23	0.3	4736	16
overall response rate definition	1.49	0.1	2848	14
overall response rate orr	0.69	1	3857	20
overall response rate cancer	1.12	1	7426	58
overall response rate objective response rate	1.23	0.7	6094	43
overall response rate vs complete response	1.94	0.7	6685	100
what is an overall response rate	1.92	1	5755	59
objective vs overall response rate	1.12	0.9	140	42
what is overall response rate in oncology	1.02	0.2	3312	75
overall response rate meaning	1.6	0.5	3325	71
how to calculate overall response rate	1.17	0.8	3865	33
overall response rate cancer definition	1.31	0.4	5959	41
what is the response rate	0.26	0.3	3309	78
response rate definition in research	1.82	0.2	6855	53

Search Results related to overall response rate on Search Engine

The Clinical Viewpoint: Definitions, Limitations of RECIST, …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844002/

WebMay 5, 2013 · Overall response rate (ORR) is defined as the proportion of patients who have a partial or complete response to therapy; it does not include stable disease and is a direct measure of drug tumoricidal activity.

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Objective response rate assessment in oncology: Current situation …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046919/

WebFeb 2, 2020 · The best overall response is a result of a combination of tumor responses in target and nontarget lesions. If there is any new lesion, the overall best response is always PD. In the absence of any new lesion, CR is the complete disappearance of all target and nontarget lesions.

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Clinical Trial Endpoints in Cancer Research: Four Terms You …
astrazeneca-us.com

https://www.astrazeneca-us.com/media/astrazeneca-us-blog/2018/clinical-trial-endpoints-in-cancer-research-four-terms-you-should-know-09242018.html

WebSep 24, 2018 · Overall response rate, or ORR, is the proportion of patients in a trial whose tumor is destroyed or significantly reduced by a drug.

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Clinical endpoints in oncology - a primer - PMC - National Center …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085844/

WebApr 15, 2021 · Introduction. Clinical trials are critical to the development of medical interventions as they assess the safety and efficacy of each new approach. A clinical endpoint is an objective tool used to measure how beneficial a medical intervention is to a patient’s feeling, function, and survival.

DA: 1 PA: 68 MOZ Rank: 39

Assessment of objective response rate (ORR) by investigator …
ascopubs.org

https://ascopubs.org/doi/10.1200/JCO.2021.39.15_suppl.e13570

WebMay 28, 2021 · e13570. Background: Objective response rate (ORR), defined as the proportion of patients with a complete response or partial response to treatment according to Response Evaluation Criteria in Solid Tumors (RECIST), is the most common endpoint used in pivotal trials supporting FDA approval of cancer drugs for solid …

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Overall Response Rate, Progression-Free Survival, and …
ascopubs.org

https://ascopubs.org/doi/pdf/10.1200/jco.2014.59.0489

WebMARCH 20 2015. JOURNAL OF CLINICAL ONCOLOGY. O R I G I N A L R E P O R T. Overall Response Rate, Progression-Free Survival, and Overall Survival With Targeted and Standard Therapies in Advanced Non–Small-Cell Lung Cancer: US Food and Drug Administration Trial-Level and Patient-Level Analyses.

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Evaluation of Overall Response Rate and Progression-Free …
aacrjournals.org

https://aacrjournals.org/clincancerres/article/24/10/2268/80764/Evaluation-of-Overall-Response-Rate-and

WebMay 14, 2018 · Evaluation of Overall Response Rate and Progression-Free Survival as Potential Surrogate Endpoints for Overall Survival in Immunotherapy Trials | Clinical Cancer Research | American Association for Cancer Research. Cancer Therapy: Clinical | …

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Overall Survival and Response with Nivolumab and Relatlimab in …
nejm.org

https://evidence.nejm.org/doi/full/10.1056/EVIDoa2200239

WebMar 22, 2023 · Results. At a median follow-up of 19.3 months, median PFS according to BICR was 10.2 months (95% confidence interval [CI], 6.5 to 14.8) with nivolumab + relatlimab versus 4.6 months (95% CI, 3.5 to...

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Local Investigators Significantly Overestimate Overall Response Rates
frontiersin.org

https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2022.858354/full

WebMay 15, 2022 · REVIEW article. Front. Pharmacol., 15 May 2022. Sec. Drugs Outcomes Research and Policies. Volume 13 - 2022 | https://doi.org/10.3389/fphar.2022.858354. Local Investigators Significantly Overestimate Overall Response Rates Compared to Blinded Independent Central Reviews in Uncontrolled Oncology Trials: A Comprehensive Review …

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Efficacy endpoints in Oncology
lexjansen.com

https://lexjansen.com/phuse/2013/is/IS01.pdf

WebBest Overall Response Rate or Objective Response Rate (ORR): the presence of at least one confirmed CR or confirmed PR Disease Control Rate: the presence of at least one confirmed CR or confirmed PR or SD OTHER RESPONSE CRITERIA FOR NON SOLID TUMORS: EXAMPLE ACUTE MYELOID LEUKEMIA (AML)

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