ABO incompatibility: MedlinePlus Medical Encyclopedia
Sep 01, 2021 · ABO incompatibility. A, B, AB, and O are the 4 major blood types. The types are based on small substances (molecules) on the surface of the blood cells. When people who have one blood type receive blood from someone with a different blood type, it may cause their immune system to react. This is called ABO incompatibility.
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