Therapeutic index - Wikipedia
https://en.wikipedia.org/wiki/Therapeutic_index
OverviewTherapeutic windowTypesDrug developmentRange of therapeutic indicesSafety ratioSynergistic effectOptimal biological doseThe therapeutic window (or pharmaceutical window) of a drug is the range of drug dosages which can treat disease effectively without having toxic effects. Medication with a small therapeutic window must be administered with care and control, frequently measuring blood concentration of the drug, to avoid harm. Medications with narrow therapeutic windows include theophylline, digoxin, lithium, and warfarin.
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