cln3 | Juvenile CLN3 Disease - Symptoms, Causes, Treatment

Keyword	CPC	PCC	Volume	Score	Length of keyword
cln3	0.6	0.9	8643	1	4

Keyword	CPC	PCC	Volume	Score
cln3	1.3	1	851	79
cln3 batten disease	1.81	0.4	4318	60
cln3 gene	0.45	0.6	4149	93
cln3 disease	1.83	0.8	8680	76
cln3 protein	0.89	0.9	8764	49
cln3240	1.47	0.5	2026	18
cln301pc	0.37	0.3	2600	6
cln3-0035h040	0.1	0.8	2616	63
cln3 treatment	1.01	0.6	2754	63
cln3-0016h090	1.78	0.2	3628	74
cln3 c.461_del677 p. gly154alafs*29	1.62	0.9	3218	69
cln3 juvenile batten disease	1.2	0.9	9962	33
cln3 batten disease life expectancy	0.2	0.3	4671	16

Search Results related to cln3 on Search Engine

Juvenile CLN3 Disease - Symptoms, Causes, Treatment | NORD
rarediseases.org

https://rarediseases.org/rare-diseases/batten-disease/

WEBOct 27, 2016 · Juvenile CLN3 disease is caused by changes (mutations) of the CLN3 gene and is inherited as an autosomal recessive trait. It is the most common form of NCL, is found worldwide, and is found particularly in families of …

DA: 37 PA: 43 MOZ Rank: 55

CLN3 disease: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/condition/cln3-disease/

WEBCLN3 disease is an inherited disorder that primarily affects the nervous system. After 4 to 6 years of normal development, children with this condition develop vision impairment, intellectual disability, movement problems, speech …

DA: 44 PA: 57 MOZ Rank: 19

CLN3 disease - About the Disease - Genetic and Rare Diseases
nih.gov

https://rarediseases.info.nih.gov/diseases/5897/cln3-disease/

WEBSummary. Neuronal ceroid lipofuscinosis 3 (CLN3-NCL) is a rare condition that affects the nervous system. Symptoms may include rapidly progressive vision loss, developmental regression (loss of acquired milestones), cognitive decline, heart problems, seizures, speech disturbances, behavioral problems (including aggression), and movement ...

DA: 24 PA: 75 MOZ Rank: 30

What is Batten? - Beyond Batten Disease Foundation
beyondbatten.org

https://beyondbatten.org/understanding-batten/what-is-batten/

WEBThe CLN3 form of Batten disease. CLN3, often called juvenile Batten disease, is an ultra-rare, fatal, inherited disorder that primarily affects the nervous system and left untreated, is fatal.

DA: 63 PA: 24 MOZ Rank: 39

Loss of the batten disease protein CLN3 leads to mis ... - Nature
nature.com

https://www.nature.com/articles/s41467-023-39643-7

WEBJul 3, 2023 · 5 Citations. 82 Altmetric. Metrics. Batten disease, one of the most devastating types of neurodegenerative lysosomal storage disorders, is caused by mutations in CLN3. Here, we show that CLN3...

DA: 36 PA: 56 MOZ Rank: 57

The CLN3 gene and protein: What we know - PMC - National …
nih.gov

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6900386/

WEBSep 30, 2019 · We believe that a strong understanding of where we are in our experimental understanding of the CLN3 gene, its regulation, gene product, protein structure, tissue distribution, biomarker use, and pathological responses to its deficiency, lays the groundwork for determining therapeutic action plans.

DA: 7 PA: 61 MOZ Rank: 40

Batten Disease: What Is It, Symptoms, Cause & Outlook - Cleveland Clinic
clevelandclinic.org

https://my.clevelandclinic.org/health/diseases/6018-batten-disease

WEBJun 10, 2021 · Batten disease is a group of fatal genetic disorders. Providers also call this group of disorders neuronal ceroid lipofuscinosis (NCL). There are 13 known types of Batten disease. All types cause many of the same symptoms. These include seizures, vision loss and cognitive (thinking and reasoning) problems.

DA: 96 PA: 31 MOZ Rank: 20

A human model of Batten disease shows role of CLN3 in ... - Nature
nature.com

https://www.nature.com/articles/s42003-021-01682-5

WEBFeb 5, 2021 · 17 Citations. 27 Altmetric. Metrics. Abstract. Mutations in CLN3 lead to photoreceptor cell loss in CLN3 disease, a lysosomal storage disorder characterized by childhood-onset vision loss,...

DA: 88 PA: 55 MOZ Rank: 60

CLN3 gene: MedlinePlus Genetics
medlineplus.gov

https://medlineplus.gov/genetics/gene/cln3/

WEBThe CLN3 gene provides instructions for making a protein that is found in tissues throughout the body, yet its function is unclear. The CLN3 protein is found in many compartments within cells, but its role in lysosomes is most well-studied. Lysosomes are cellular compartments that digest and recycle different types of molecules.

DA: 81 PA: 12 MOZ Rank: 71

The CLN3 gene and protein: What we know - PubMed
nih.gov

https://pubmed.ncbi.nlm.nih.gov/31568712/

WEBWe believe that a strong understanding of where we are in our experimental understanding of the CLN3 gene, its regulation, gene product, protein structure, tissue distribution, biomarker use, and pathological responses to its deficiency, lays the groundwork for determining therapeutic action plans.

DA: 98 PA: 33 MOZ Rank: 79