Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500874/
Apr 28, 2017 · Atrial substrates that promote reentry are characterized by abnormalities of the atrial cardiomyocyte, fibrotic changes, and alterations in the interstitial matrix with primarily non-collagen deposits. 5 These molecular and histologic changes impair normal anisotropic conduction (fibrosis and/or reduced cell coupling) and may shorten atrial ERP.
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