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Ibuprofen is the most commonly used OTC arthritis medication and is available in non-prescription strength, including tablets and fast release capsules, which may last four to six hours. Naproxen sodium is available non-prescription strength as an over-the-counter remedy for arthritis.What is the best arthritis cream for knees?
Diclofenac sodium 2% liquid (Pennsaid). When used for osteoarthritis knee pain, apply 40 mg (2 pumps) on each painful knee, 2 times a day. Diclofenac sodium 3% gel (Solaraze). This strength gel is approved for use in treating actinic keratosis, a skin condition. It has not been approved for use in arthritis.